产品名称 | LIN7BHuman Recombinant Protein |
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产品描述 | LIN7B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 230 amino acids (1-207 a.a.) and having a molecular mass of 25.3kDa. LIN7B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | LIN7BHuman Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9HAP6) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile filtered colorless solution. |
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内容 | LIN7B protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | LIN7B |
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基因全名 | Protein lin-7 homolog B |
蛋白功能 | Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity). |
Uniprot ID | LIN7B: Q9HAP6 |
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