LGMN Legumain Human Recombinant Protein 1mg

产品概况

产品名称	LGMN Legumain Human Recombinant Protein
产品描述	LGMN produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (18-433 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 422 amino acids and having a molecular mass of 48.4kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). LGMN is purified by proprietary chromatographic techniques.
文献引用格式	LGMN Legumain Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ99538)
应用范围	Cell Culture
抗体来源	No

产品名称

LGMN Legumain Human Recombinant Protein

产品描述

LGMN produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (18-433 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 422 amino acids and having a molecular mass of 48.4kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).
LGMN is purified by proprietary chromatographic techniques.

文献引用格式

LGMN Legumain Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ99538)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile filtered colorless solution.
内容	LGMN protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile filtered colorless solution.

内容

LGMN protein solution (1mg/ml) contains Phosphate buffered saline (pH7.4) and 10% glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	LGMN
基因全名	Legumain
蛋白功能	Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Tissue Specificity	Ubiquitous. Particularly abundant in kidney, heart and placenta.
Uniprot ID	LGMN: Q99538

基因名

LGMN

基因全名

Legumain

蛋白功能

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Tissue Specificity

Ubiquitous. Particularly abundant in kidney, heart and placenta.

Uniprot ID

LGMN: Q99538

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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