产品名称 | GPN1 GPN-loop GTPase 1 Human Recombinant Protein |
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产品描述 | GPN1 Human Recombinant produced in E. coli is a single polypeptide chain containing 398 amino acids (1-374) and having a molecular mass of 44.3 kDa. GPN1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | GPN1 GPN-loop GTPase 1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9HCN4) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | The GPN1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 50mM NaCl, 1mM DTT and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | GPN1 |
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基因全名 | GPN-loop GTPase 1 |
蛋白功能 | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). |
Tissue Specificity | Expressed ubiquitously. |
Uniprot ID | GPN1: Q9HCN4 |
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