GLRX2 Glutaredoxin 2 Human Recombinant Protein 1mg

产品概况

产品名称	GLRX2 Glutaredoxin 2 Human Recombinant Protein
产品描述	Glutaredoxin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 154 amino acids (20-164 a.a.) and having a molecular mass of 17 kDa. The GRX2 is fused to 8 amino acid His tag at C-Terminus.
文献引用格式	GLRX2 Glutaredoxin 2 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9NS18)
应用范围	Cell Culture
抗体来源	No

产品名称

GLRX2 Glutaredoxin 2 Human Recombinant Protein

产品描述

Glutaredoxin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 154 amino acids (20-164 a.a.) and having a molecular mass of 17 kDa. The GRX2 is fused to 8 amino acid His tag at C-Terminus.

文献引用格式

GLRX2 Glutaredoxin 2 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9NS18)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile Filtered clear colorless solution.
内容	Glutaredoxin-2 solution contains 20mM Tris-HCl pH-8 & 0.1mM PMSF and 10% glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile Filtered clear colorless solution.

内容

Glutaredoxin-2 solution contains 20mM Tris-HCl pH-8 & 0.1mM PMSF and 10% glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	GLRX2
基因全名	Glutaredoxin-2, mitochondrial
蛋白功能	Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
Tissue Specificity	Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta and lung. Not expressed in peripheral blood leukocytes.
Uniprot ID	GLRX2: Q9NS18

基因名

GLRX2

基因全名

Glutaredoxin-2, mitochondrial

蛋白功能

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

Tissue Specificity

Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta and lung. Not expressed in peripheral blood leukocytes.

Uniprot ID

GLRX2: Q9NS18

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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