产品名称 | GDNF Glial-Derived Neurotrophic Factor Human Recombinant Protein |
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产品描述 | Glial derived Neurotrophic Factor Human Recombinant produced in E.Coli is a non-glycosylated disulfide-linked homodimer containing 2 x 135 amino acids and having a total molecular mass of approximately 30kDa. GDNF is purified by proprietary chromatographic techniques. |
文献引用格式 | GDNF Glial-Derived Neurotrophic Factor Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP39905) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered White lyophilized (freeze-dried) powder. |
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储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | GDNF |
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基因全名 | Glial cell line-derived neurotrophic factor |
蛋白功能 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
Tissue Specificity | In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. |
Uniprot ID | GDNF: P39905 |
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