产品名称 | G3BP1 GTPase Activating Protein (SH3 domain) Binding Protein 1 Human Recombinant Protein |
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产品描述 | G3BP1 Human Recombinant fused with an 8 amino acid His tag at C-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 474 amino acids (1-466 a.a.) and having a molecular mass of 53.2kDa. The G3BP1 is purified by proprietary chromatographic techniques. |
文献引用格式 | G3BP1 GTPase Activating Protein (SH3 domain) Binding Protein 1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ13283) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | The G3BP1 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT and 100mM NaCl. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | G3BP1 |
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基因全名 | Ras GTPase-activating protein-binding protein 1 |
蛋白功能 | May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium- dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. |
Tissue Specificity | Ubiquitous. |
Uniprot ID | G3BP1: Q13283 |
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