产品名称 | FOLR1 Human, Folate Receptor 1 Human Recombinant Protein, sf9 |
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产品描述 | FOLR1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 218 amino acids (26-234a.a.) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). FOLR1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
文献引用格式 | FOLR1 Human, Folate Receptor 1 Human Recombinant Protein, sf9 (Boster Biological Technology, Wuhan, China. Catalog #PROTP15328-1) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | FOLR1 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | FOLR1 |
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基因全名 | Folate receptor alpha |
蛋白功能 | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. |
Tissue Specificity | Primarily expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum. Detected in placenta and thymus epithelium. |
Uniprot ID | FOLR1: P15328 |
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