FLRT3 Fibronectin Leucine Rich Transmembrane Protein 3 Human Recombinant Protein 10ug

产品概况

产品名称	FLRT3 Fibronectin Leucine Rich Transmembrane Protein 3 Human Recombinant Protein
产品描述	FLRT3 produced in Sf9 insect cells is a single, glycosylated polypeptide chain containing 508 amino acids (29-528a.a.) and having a molecular mass of 57.6kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa). FLRT3 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
文献引用格式	FLRT3 Fibronectin Leucine Rich Transmembrane Protein 3 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9NZU0)
应用范围	Cell Culture
抗体来源	No

产品名称

FLRT3 Fibronectin Leucine Rich Transmembrane Protein 3 Human Recombinant Protein

产品描述

FLRT3 produced in Sf9 insect cells is a single, glycosylated polypeptide chain containing 508 amino acids (29-528a.a.) and having a molecular mass of 57.6kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).
FLRT3 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

文献引用格式

FLRT3 Fibronectin Leucine Rich Transmembrane Protein 3 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9NZU0)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterilefiltered colorless solution.
内容	FLRT3 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterilefiltered colorless solution.

内容

FLRT3 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	FLRT3
基因全名	Leucine-rich repeat transmembrane protein FLRT3
蛋白功能	Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).
Tissue Specificity	Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.
Uniprot ID	FLRT3: Q9NZU0

基因名

FLRT3

基因全名

Leucine-rich repeat transmembrane protein FLRT3

蛋白功能

Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).

Tissue Specificity

Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart.

Uniprot ID

FLRT3: Q9NZU0

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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