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| 产品名称 | Flavokinase Riboflavin Kinase Human Recombinant Protein |
|---|---|
| 产品描述 | Flavokinase Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 182 amino acids (1-162 a.a.) and having a molecular mass of 20.5kDa. Flavokinase is fused to 20 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
| 文献引用格式 | Flavokinase Riboflavin Kinase Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ969G6) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Sterile filtered colorless solution. |
|---|---|
| 内容 | The Flavokinase solution containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. *可以提供无载体抗体。 |
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | RFK |
|---|---|
| 基因全名 | Riboflavin kinase |
| 蛋白功能 | Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. |
| Tissue Specificity | Detected in brain, placenta and urinary bladder. |
| Uniprot ID | RFK: Q969G6 |
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