FKBP6 FK506 Binding Protein 6 Human Recombinant Protein 2ug

产品概况

产品名称	FKBP6 FK506 Binding Protein 6 Human Recombinant Protein
产品描述	FKBP6 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 347 amino acids (1-327 a.a.) and having a molecular mass of 39.3 kDa. FKBP6 protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
文献引用格式	FKBP6 FK506 Binding Protein 6 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTO75344)
应用范围	Cell Culture
抗体来源	No

产品名称

FKBP6 FK506 Binding Protein 6 Human Recombinant Protein

产品描述

FKBP6 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 347 amino acids (1-327 a.a.) and having a molecular mass of 39.3 kDa. FKBP6 protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.

文献引用格式

FKBP6 FK506 Binding Protein 6 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTO75344)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile filtered colorless solution.
内容	FKBP6 Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, 1mM EDTA, 50mM NaCl & 40% glycerol. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile filtered colorless solution.

内容

FKBP6 Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, 1mM EDTA, 50mM NaCl & 40% glycerol.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	FKBP6
基因全名	Inactive peptidyl-prolyl cis-trans isomerase FKBP6
蛋白功能	Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).
Tissue Specificity	Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
Uniprot ID	FKBP6: O75344

基因名

FKBP6

基因全名

Inactive peptidyl-prolyl cis-trans isomerase FKBP6

蛋白功能

Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).

Tissue Specificity

Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.

Uniprot ID

FKBP6: O75344

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

办公用品