产品名称 | FKBP4 FK506 Binding Protein 4 Human Recombinant Protein |
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产品描述 | FKBP4 produced in E.Coli is a single,non-glycosylated polypeptide chain containing 479 amino acids (1-459 a.a.) and having a molecular mass of 53.9 kDa. FKBP4 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. |
文献引用格式 | FKBP4 FK506 Binding Protein 4 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ02790) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile filtered colorless solution. |
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内容 | The FKBP4 protein solution contains 20mM Tris-HCl, pH-8 and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | FKBP4 |
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基因全名 | Peptidyl-prolyl cis-trans isomerase FKBP4 |
蛋白功能 | Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria. |
Tissue Specificity | Widely expressed. |
Uniprot ID | FKBP4: Q02790 |
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