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| 产品名称 | FKBP1A FK506 Binding Protein 1A Human Recombinant Protein |
|---|---|
| 产品描述 | FKPB1A Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain purified through a Ni2+-affinity chromatography followed by gel filtration. |
| 文献引用格式 | FKBP1A FK506 Binding Protein 1A Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP62942) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Sterile Filtered colorless solution. |
|---|---|
| 内容 | The FKBP1A protein solution contains 50mM Hepes pH-8.0, 150mM NaCl, 0.5mM EDTA & 1mM sodium azide. *可以提供无载体抗体。 |
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | FKBP1A |
|---|---|
| 基因全名 | Peptidyl-prolyl cis-trans isomerase FKBP1A |
| 蛋白功能 | Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Uniprot ID | FKBP1A: P62942 |
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