产品名称 | FGG Fibrinogen Gamma Chain Human Recombinant Protein |
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产品描述 | FGG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 434 amino acids (27-437 a.a) and having a molecular mass of 48.9kDa. FGG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | FGG Fibrinogen Gamma Chain Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP02679) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered clear solution. |
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内容 | FGG protein solution (0.5mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | FGG |
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基因全名 | Fibrinogen gamma chain |
蛋白功能 | Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. |
Tissue Specificity | Detected in blood plasma (at protein level). |
Uniprot ID | FGG: P02679 |
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