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| 产品名称 | FGF-23-C-term Fibroblast Growth Factor-23 C-Terminal Human Recombinant Protein |
|---|---|
| 产品描述 | FGF-23 C-term Protein is 8.67 kDa protein containing 72 amino acid residues and an additional 9 a.a. His-Tag at N-terminus. |
| 文献引用格式 | FGF-23-C-term Fibroblast Growth Factor-23 C-Terminal Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9GZV9-1) |
| 应用范围 | Cell Culture |
| 抗体来源 | No |
| 产品形态 | Filtered White lyophilized (freeze-dried) powder. |
|---|---|
| 储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
| 基因名 | FGF23 |
|---|---|
| 基因全名 | Fibroblast growth factor 23 |
| 蛋白功能 | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. |
| Tissue Specificity | Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts). |
| Uniprot ID | FGF23: Q9GZV9 |
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