产品名称 | FGF-23 Fibroblast Growth Factor-23 Human Recombinant Protein, His Tag |
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产品描述 | Fibroblast Growth Factor-23 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain expressed with a -6xHis tag containing a total of 257 amino acids (251 a.a. FGF23+ 6 a.a. His tag) and having a molecular mass of 28629.5 Dalton. The FGF-23 is and purified by chromatographic techniques. |
文献引用格式 | FGF-23 Fibroblast Growth Factor-23 Human Recombinant Protein, His Tag (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9GZV9-2) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered white lyophilized powder. |
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内容 | The protein (0.5mg/ml) was lyophilized from 25mM Tris pH7.5 and 0.6M NaCl solution. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | FGF23 |
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基因全名 | Fibroblast growth factor 23 |
蛋白功能 | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. |
Tissue Specificity | Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts). |
Uniprot ID | FGF23: Q9GZV9 |
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