产品名称 | CCM2 Cerebral Cavernous Malformation 2 Human Recombinant Protein |
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产品描述 | CCM2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 311 amino acids (66-353 a.a) and having a molecular mass of 34.3kDa.CCM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | CCM2 Cerebral Cavernous Malformation 2 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTQ9BSQ5) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered clear solution. |
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内容 | CCM2 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | CCM2 |
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基因全名 | Cerebral cavernous malformations 2 protein |
蛋白功能 | Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity). |
Uniprot ID | CCM2: Q9BSQ5 |
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