产品名称 | CBX5 Chromobox Homolog 5 Human Recombinant Protein |
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产品描述 | CBX5 Human Recombinant produced in E. coli is a single polypeptide chain containing 215 amino acids (1-191) and having a molecular mass of 24.8kDa. CBX5 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
文献引用格式 | CBX5 Chromobox Homolog 5 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP45973) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | The CBX5 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 30% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | CBX5 |
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基因全名 | Chromobox protein homolog 5 |
蛋白功能 | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
Uniprot ID | CBX5: P45973 |
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