产品名称 | CBR1 Carbonyl Reductase-1 Human Recombinant Protein |
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产品描述 | Recombinant Human CBR1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 277 amino acids (1-277 a.a) and having a molecular mass of 30 kDa. CBR1 is purified by proprietary chromatographic techniques. |
文献引用格式 | CBR1 Carbonyl Reductase-1 Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTP16152) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile filtered colorless solution. |
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内容 | The CBR1 protein contains 20mM Tris-HCl buffer pH-8.5, and 10% glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | CBR1 |
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基因全名 | Carbonyl reductase [NADPH] 1 |
蛋白功能 | NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. |
Uniprot ID | CBR1: P16152 |
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