产品名称 | ADAM12 A Disintegrin and Metalloproteinase Domain 12 S-Isoform Human Recombinant Protein |
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产品描述 | ADAM12 Short/soluble isoform Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 531 amino acids (208-738) and having a molecular mass of 62 kDa. |
文献引用格式 | ADAM12 A Disintegrin and Metalloproteinase Domain 12 S-Isoform Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTO43184) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Sterile Filtered colorless solution. |
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内容 | The ADAM12 solution contains 25mM Sodium Acetate pH 4.8 and 50% Glycerol. *可以提供无载体抗体。 |
储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | ADAM12 |
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基因全名 | Disintegrin and metalloproteinase domain-containing protein 12 |
蛋白功能 | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). |
Tissue Specificity | Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas. |
Uniprot ID | ADAM12: O43184 |
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