产品名称 | Acrp30 Human, Adiponectin Human Recombinant Protein, Trimeric form |
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产品描述 | Trimeric form of Adiponectin Human trimeric form was expressed in HEK293 cells. The cysteine 39 was replaced with Alanine (C39A) 9. hAd-C39A can only form a trimer, but not a hexamer or an HMW form. |
文献引用格式 | Acrp30 Human, Adiponectin Human Recombinant Protein, Trimeric form (Boster Biological Technology, Wuhan, China. Catalog #PROTQ15848-2) |
应用范围 | Cell Culture |
抗体来源 | No |
产品形态 | Filtered White lyophilized (freeze-dried) powder. |
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储存条件 | Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles. |
基因名 | ADIPOQ |
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基因全名 | Adiponectin |
蛋白功能 | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
Tissue Specificity | Synthesized exclusively by adipocytes and secreted into plasma. |
Uniprot ID | ADIPOQ: Q15848 |
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