(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein 2ug

产品概况

产品名称	(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein
产品描述	RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
文献引用格式	(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTO75771-1)
应用范围	Cell Culture
抗体来源	No

产品名称

(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein

产品描述

RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

文献引用格式

(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein (Boster Biological Technology, Wuhan, China. Catalog #PROTO75771-1)

应用范围

Cell Culture

抗体来源

产品详情

产品形态	Sterile Filtered colorless solution.
内容	RAD51D (1-328) solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT. *可以提供无载体抗体。
储存条件	Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

产品形态

Sterile Filtered colorless solution.

内容

RAD51D (1-328) solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
*可以提供无载体抗体。

储存条件

Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.

指标相关信息 (来源: Uniprot.org)

基因名	RAD51D
基因全名	DNA repair protein RAD51 homolog 4
蛋白功能	Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single- stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single- stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
Tissue Specificity	Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.
Uniprot ID	RAD51D: O75771

基因名

RAD51D

基因全名

DNA repair protein RAD51 homolog 4

蛋白功能

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single- stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single- stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Tissue Specificity

Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.

Uniprot ID

RAD51D: O75771

实验耗材

分子生物学试剂

蛋白与免疫学

生化试剂

细胞及检测试剂

色谱及层析

仪器设备

实验服务

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