货号 | EK1533-RB |
产品名称 | Rabbit GREM2 PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit GREM2. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: E.coli; Immunogen sequence: R22-Q168 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <12pg/ml |
检测范围 | 62.5pg/ml-4000pg/ml |
基因名称 | GREM2 |
基因全名 | Gremlin-2 |
Uniprot ID | Q9H772 |
指标别名 | Gremlin-2;Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;Protein related to DAN and cerberus;GREM2;CKTSF1B2, DAND3, PRDC; |
背景资料 | GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43. |
显色时间 | 15-20 |