| 货号 | EK0921-PR |
| 产品名称 | Monkey primate TNFSF13/APRIL PicoKine™ ELISA Kit |
| 产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate TNFSF13/APRIL. 96wells/kit, with removable strips. |
| 免疫原 | Expression system for standard: NSO,A105-L250 |
| 交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
| 敏感性 | <10pg/ml |
| 检测范围 | 156pg/ml-10,000pg/ml |
| 基因名称 | TNFSF13 |
| 基因全名 | tumor necrosis factor (ligand) superfamily, member 13 |
| Uniprot ID | Q2QBA2 |
| 指标别名 | Tumor necrosis factor (Ligand) superfamily member 13 transcript variant delta ;Tumor necrosis factor ligand superfamily member 13 ;TNFSF13 ; |
| 背景资料 | Tumor necrosis factor ligand superfamily member 13(TNFSF13) also known as a proliferation-inducing ligand(APRIL) is a protein that in humans is encoded by the TNFSF13 gene. TNFSF13 has also been designated CD256(cluster of differentiation 256). The protein encoded by this gene is a member of the tumor necrosis factor ligand(TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vivo experiments suggest an important role for APRIL in the long-term survival of plasma cells in the bone marrow. Mice deficient in April showed a reduced ability to support plasma cell survival In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such asTNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The TNFSF13 gene lies 878 bp downstream of the TNFSF12 gene on chromosome 17p13.1. |
| 显色时间 | 20-25 |
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