货号 | EK0641-PR |
产品名称 | Monkey primate Survivin PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate Survivin. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: E.coli; Immunogen sequence: M1-D142 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <2pg/ml |
检测范围 | 62.5pg/ml-4000pg/ml |
基因名称 | BIRC5 |
基因全名 | Baculoviral IAP repeat-containing protein 5 |
Uniprot ID | O15392 |
指标别名 | Baculoviral IAP repeat-containing protein 5;Apoptosis inhibitor 4;Apoptosis inhibitor survivin;BIRC5;API4, IAP4; |
背景资料 | Survivin(also termed API4) belongs to the family of genes known as inhibitors of apoptosis, and it has been implicated in both prevention of cell death and control of mitosis. Survivin is prominently expressed in transformed cell lines and in all the most common monkey primate cancers of lung, colon, pancreas, prostate and breast in vivo. It is also found in approximately 50% of high-grade non-Hodgkin's lymphomas. Survivin encodes a deduced 142-amino acid protein and localizes on chromosome 17q25. The overexpression of it in cancer may overcome an apoptotic checkpoint and favour aberrant progression of transformed cells through mitosis. The standard product used in this kit is recombinant monkey primate Survivin with the molecular mass of 34 KDa. |
显色时间 | 25-30 |