货号 | EK1285-PR |
产品名称 | Monkey primate CXCL14/Brak PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate CXCL14. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: E.coli; Immunogen sequence: S35-E111 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 62.5pg/ml-4000pg/ml |
基因名称 | CXCL14 |
基因全名 | C-X-C motif chemokine 14 |
Uniprot ID | O95715 |
指标别名 | C-X-C motif chemokine 14;Chemokine BRAK;MIP-2G;Small-inducible cytokine B14;CXCL14;MIP2G, NJAC, SCYB14;PSEC0212, UNQ240/PRO273; |
背景资料 | Chemokine(C-X-C motif) ligand 14(CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK(for breast and kidney-expressed chemokine). This gene is mapped to 5q31.1. CXCL14 is constitutively expressed at high levels in many normal tissues, it has been found that fibroblasts are the primary source of CXCL14 and that CXCL14 is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. It is also a potent chemoattractant and activator of dendritic cells, is implicated in homing of these cells, and can stimulate the migration of activated NK cells. CXCL14 also inhibits angiogenesis, possibly as a result of its ability to block endothelial cell chemotaxis. In addition to it, CXCL14 is a potent chemokine for immature DCs, with a chemoattractive activity comparable to bacterial fMLP and MIP1A. |
显色时间 | 20-25 |