货号 | EK0523-EQ |
产品名称 | Horse equine TIMP-3 PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine TIMP-3. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: NSO; Immunogen sequence: C24-P211 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <2pg/ml |
检测范围 | 156pg/ml-10,000pg/ml |
基因名称 | TIMP3 |
基因全名 | Metalloproteinase inhibitor 3 |
Uniprot ID | P35625 |
指标别名 | Metalloproteinase inhibitor 3;Protein MIG-5;Tissue inhibitor of metalloproteinases 3;TIMP-3;TIMP3; |
背景资料 | The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD). |
显色时间 | 15-20 |