| 货号 | EK1103-EQ |
| 产品名称 | Horse equine TGF-Beta 3 PicoKine™ ELISA Kit |
| 产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated horse equine TGF-beta 3. 96wells/kit, with removable strips. |
| 免疫原 | Expression system for standard: sf21; Immunogen sequence: A301-S412 |
| 交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
| 敏感性 | <10pg/ml |
| 检测范围 | 31.2pg/ml-2000pg/ml |
| 基因名称 | TGFB3 |
| 基因全名 | Transforming growth factor beta-3 |
| Uniprot ID | P10600 |
| 指标别名 | Transforming growth factor beta-3;TGF-beta-3;Latency-associated peptide;LAP;TGFB3; |
| 背景资料 | Transforming growth factor beta 3(TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix(ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin(CTNNB1) via nuclear phospho-Smad2 and Smad4. |
| 显色时间 | 20-25 |
新浪微博
腾讯微博
QQ空间
客服
