货号 | EK0945-EQ |
产品名称 | Horse equine Endothelin PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine Endothelin. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: horse equine peptide; Immunogen sequence: C53-W73 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <0.5pg/ml |
检测范围 | 3.9pg/ml-250pg/ml |
基因名称 | EDN1 |
基因全名 | Endothelin-1 |
Uniprot ID | P05305 |
指标别名 | Endothelin-1;Preproendothelin-1;PPET1;Endothelin-1;ET-1;Big endothelin-1;EDN1; |
背景资料 | The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of horse equine endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure(hypertension) and heart disease. |
显色时间 | 20-25 |