货号 | EK0380-HA |
产品名称 | Chinese Hamster IGF-2 PicoKine™ ELISA Kit |
产品描述 | Sandwich High Sensitivity ELISA kit for Quantitative Detection of Chinese hamster IGF-2. 96wells/kit, with removable strips. |
免疫原 | Expression system for standard: E.coli; Immunogen sequence: A25-E91 |
交叉反应 | There is no detectable cross-reactivity with IGF-1. |
敏感性 | <5pg/ml |
检测范围 | 62.5pg/ml-4000pg/ml |
基因名称 | Igf2 |
基因全名 | Insulin-like growth factor II |
Uniprot ID | P01346 |
指标别名 | Insulin-like growth factor II;IGF-II;Multiplication-stimulating activity;MSA;Multiplication-stimulating polypeptide;Insulin-like growth factor II;Preptin;Igf2;Igf-2; |
背景资料 | Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland. |
显色时间 | 25-30 |