货号 | EK1899 |
产品名称 | Mouse Podocalyxin PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse Podocalyxin in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | NSO, H22-S404 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 156pg/ml-10000pg/ml |
基因名称 | Podxl |
基因全名 | podocalyxin-like |
Uniprot ID | Q9R0M4 |
指标别名 | Podocalyxin; Podocalyxin-like protein 1; PC; PCLP-1; Podxl; Pclp1 |
背景资料 | Podocalyxin-like protein 1 is a protein that in humans is encoded by the PODXL gene. It is mapped to 6 A3.3; 6 12.57 Cm. This gene encodes a member of the CD34 sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Inactivation of the encoding gene in mice leads to anuria, omphalocele and perinatal death. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. |
显色时间 | 15-20 |