货号 | EK1854 |
产品名称 | Mouse PDGF-CC PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse PDGF-CC in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | E.coli, V235-G345 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 15.6pg/ml-1000pg/ml |
基因名称 | Pdgfc |
基因全名 | platelet-derived growth factor, C polypeptide |
Uniprot ID | Q8CI19 |
指标别名 | Platelet-derived growth factor C; PDGF-C; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-E; Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form; Pdgfc; Scdgf |
背景资料 | Platelet-derived growth factor C, also known as PDGF-C, is a 345-amino acid protein that in humans is encoded by the PDGFC gene. It is mapped to 3; 3 E3. Platelet-derived growth factors are important in connective tissue growth, survival and function, and consist of disulphide-linked dimers involving two polypeptide chains, PDGF-A and PDGF-B. PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique two-domain structure and expression pattern. PDGF-C was not previously identified with PDGF-A and PDGF-B, possibly because it may be that it is synthesized and secreted as a latent growth factor, requiring proteolytic removal of the N-terminal CUB domain for receptor binding and activation. |
显色时间 | 15-20 |