货号 | EK2015 |
产品名称 | Mouse Midkine PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse Midkine in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
免疫原 | E.coli, K23-D140 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 15.6pg/ml-1000pg/ml |
基因名称 | Mdk |
基因全名 | midkine |
Uniprot ID | P12025 |
指标别名 | Midkine; MK; Retinoic acid-induced differentiation factor; Mdk; Mk |
背景资料 | Midkine (MK) is a member of a family of neurotrophic and developmentally-regulated heparin-binding molecules that currently consists of midkine, pleiotrophin/PTN and avian RI-HB. This gene is mapped to 2 E1; 2 50.63 cM. This gene encodes a secreted growth factor that belongs to the pleiotrophin/midkine heparin-binding protein family and functions in a variety of biological processes. The encoded cytokine promotes the growth, differentiation, survival and migration of several target cells including leucocytes involved in inflammation. This protein plays a role in the formation of scar tissue and intraperitoneal adhesions, and promotes neurite outgrowth and neuron survival. The protein encoded by this gene is associated with obesity and inhibition of insulin signaling in fat cells. A pseudogene of this gene is present on chromosome 11. Alternative splicing results in multiple transcript variants. |
显色时间 | 15-20 |