货号 | EK2107 |
产品名称 | Mouse KLKB1 PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse KLKB1 in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
免疫原 | NSO, G20-A638 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 156pg/ml-10000pg/ml |
基因名称 | KLKB1 |
基因全名 | kallikrein B1 |
Uniprot ID | P03952 |
指标别名 | Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein; PKK; Plasma kallikrein heavy chain; Plasma kallikrein light chain; KLKB1; KLK3 |
背景资料 | Plasma kallikrein is a protein that in humans is encoded by the KLKB1 gene. It is mapped to 4q35.2. This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. |
显色时间 | 25-30 |