货号 | EK1923 |
产品名称 | Mouse CLEC7A PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse CLEC7A in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | NSO, G71-L244 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 62.5pg/ml-4000pg/ml |
基因名称 | Clec7a |
基因全名 | C-type lectin domain family 7, member a |
Uniprot ID | Q6QLQ4 |
指标别名 | C-type lectin domain family 7 member A; Beta-glucan receptor; C-type lectin superfamily member 12; Dendritic cell-associated C-type lectin 1; DC-associated C-type lectin 1; Dectin-1; CD369; Clec7a; Bgr; Clecsf12; Dectin1 |
背景资料 | C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene. This gene is mapped to 6; 6 F3. CLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Expression is found on myeloid dendritic cells, monocytes, macrophages and B cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. |
显色时间 | 15-20 |