货号 | EK2040 |
产品名称 | Mouse ANGPTL2 PicoKine ELISA Kit |
产品描述 | For quantitative detection of mouse ANGPTL2 in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | NSO, A20-H493 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 15.6pg/ml-1000pg/ml |
基因名称 | Angptl2 |
基因全名 | angiopoietin-like 2 |
Uniprot ID | Q9R045 |
指标别名 | Angiopoietin-related protein 2; Angiopoietin-like protein 2; Angptl2; Arp2 |
背景资料 | Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene. This gene is mapped to 2; 2 B. Angiopoietin-like protein 2 maintains tissue homeostasis by promoting adaptive inflammation and subsequent tissue reconstruction, whereas an excess of ANGPTL2 activation induced by prolonged stress promotes the breakdown of tissue homeostasis due to chronic inflammation, promoting the development of metabolic diseases. ANGPTL2 has a role also in angiogenesis, in tissue repair, in obesity, in atherosclerotic diseases and finally in carcinogenesis. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. |
显色时间 | 15-20 |