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| 货号 | EK2004 |
|---|---|
| 产品名称 | Human TNFRSF21/DR6 PicoKine ELISA Kit |
| 产品描述 | For quantitative detection of human TNFRSF21 in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
| 免疫原 | NSO, Q42-H349 |
| 交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
| 敏感性 | <10pg/ml |
| 检测范围 | 15.6pg/ml-1000pg/ml |
| 基因名称 | TNFRSF21 |
| 基因全名 | TNF receptor superfamily member 21 |
| Uniprot ID | O75509 |
| 指标别名 | Tumor necrosis factor receptor superfamily member 21; Death receptor 6; CD358; TNFRSF21; DR6; UNQ437; PRO868 |
| 背景资料 | Death receptor 6 (DR6), also known as tumor necrosis factor receptor superfamily member 21 (TNFRSF21), is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the JNK and NF-κB pathways. This gene is mapped to 6p12.3. This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
| 显色时间 | 15-20 |
| SKU | 名称 | 数量 |
| Catalog number | Description | Quantity |
| EK2004-CAP | 96-well plate precoated with anti- human TNFRSF21/DR6 antibody | 1 |
| EK2004-ST | Lyophilized recombinant human TNFRSF21/DR6 standard | 10ng/tube×2 |
| EK2004-DA | Biotinylated anti- human TNFRSF21/DR6 antibody | 130μl(dilution 1:100) |
| AR1103 | Avidin-Biotin-Peroxidase Complex (ABC) | 130μl(dilution 1:100) |
| AR1106-1 | Sample diluent buffer | 30ml |
| AR1106-2 | Antibody diluent buffer | 12ml |
| AR1106-3 | ABC diluent buffer | 12ml |
| AR1104 | TMB color developing agent | 10ml |
| AR1105 | TMB stop solution | 10ml |
| PLA-SEA | Adhesive cover | 4 |
| Intra-Assay Precision | Inter-Assay Precision | |||||
| Sample | 1 | 2 | 3 | 1 | 2 | 3 |
| n | 16 | 16 | 16 | 24 | 24 | 24 |
| Mean(pg/ml) | 21 | 94 | 378 | 26 | 103 | 431 |
| Standard deviation | 0.86 | 5.83 | 17.01 | 1.22 | 6.59 | 23.27 |
| CV(%) | 4.1% | 6.2% | 4.5% | 4.7% | 6.4% | 5.4% |
| Concentration(pg/ml) | 0 | 15.6 | 31.2 | 62.5 | 125 | 250 | 500 | 1000 |
| O.D. | 0.033 | 0.081 | 0.130 | 0.220 | 0.408 | 0.793 | 1.392 | 2.219 |
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