货号 | EK1968 |
产品名称 | Human Serpin D1 PicoKine ELISA Kit |
产品描述 | For quantitative detection of human Serpin D1 in cell culture supernates, serum and plasma (EDTA, citrate) and urine. |
免疫原 | NSO, G20-S499 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <0.1ng/ml |
检测范围 | 0.78ng/ml-50ng/ml |
基因名称 | SERPIND1 |
基因全名 | serpin family D member 1 |
Uniprot ID | P05546 |
指标别名 | Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1; HCF2 |
背景资料 | Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that inhibits IIa, and is a cofactor for heparin and dermatan sulfate. It is mapped to 22q11.21. This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. |
显色时间 | 15-20 |