货号 | EK1873 |
产品名称 | Human PZP PicoKine ELISA Kit |
产品描述 | For quantitative detection of human PZP in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | NSO, T26-V1482 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 156pg/ml-10000pg/ml |
基因名称 | PZP |
基因全名 | PZP, alpha-2-macroglobulin like |
Uniprot ID | P20742 |
指标别名 | Pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; PZP; CPAMD6 |
背景资料 | Pregnancy zone protein (PZP) is a protein which in humans is encoded by the PZP gene on chromosome 12. It is mapped to 12p13.31. The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients. |
显色时间 | 15-20 |