货号 | EK1975 |
产品名称 | Human PROC/Protein C PicoKine ELISA Kit |
产品描述 | For quantitative detection of human PROC/Protein C in cell culture supernates, serum and plasma (heparin, EDTA) and urine. |
免疫原 | NSO, A43-P461 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <0.1ng/ml |
检测范围 | 0.78ng/ml-50ng/ml |
基因名称 | Proc |
基因全名 | protein C, inactivator of coagulation factors Va and VIIIa |
Uniprot ID | P33587 |
指标别名 | Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; Proc |
背景资料 | Protein C(PROC), also called PC, is a zymogenic (inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped to 2q14.3. This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombinthrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis. |
显色时间 | 20-25 |