货号 | EK2110 |
产品名称 | Human PRELP PicoKine ELISA Kit |
产品描述 | For quantitative detection of human PRELP in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
免疫原 | NSO, Q21-I382 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 93.8pg/ml-6000pg/ml |
基因名称 | PRELP |
基因全名 | proline and arginine rich end leucine rich repeat protein |
Uniprot ID | P51888 |
指标别名 | Prolargin; Proline-arginine-rich end leucine-rich repeat protein; PRELP; SLRR2A |
背景资料 | Prolargin is a protein that in humans is encoded by the PRELP gene. It is mapped to 1q32.1. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. |
显色时间 | 25-30 |