货号 | EK1851 |
产品名称 | Human EDAR PicoKine ELISA Kit |
产品描述 | For quantitative detection of human EDAR in cell culture supernates, serum and plasma (heparin, EDTA). |
免疫原 | E.coli, E27-A187 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 15.6pg/ml-1000pg/ml |
基因名称 | EDAR |
基因全名 | ectodysplasin A receptor |
Uniprot ID | Q9UNE0 |
指标别名 | Tumor necrosis factor receptor superfamily member EDAR; Anhidrotic ectodysplasin receptor 1; Downless homolog; EDA-A1 receptor; Ectodermal dysplasia receptor; Ectodysplasin-A receptor; EDAR; DL |
背景资料 | Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. It is mapped to 2q13. This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. |
显色时间 | 15-20 |