货号 | EK2049 |
产品名称 | Human CD206/CLEC13D PicoKine ELISA Kit |
产品描述 | For quantitative detection of human CD206/CLEC13D in cell culture supernates, serum and plasma (heparin, EDTA, citrate). |
免疫原 | NSO, L19-K1383 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <50pg/ml |
检测范围 | 0.78ng/ml-50ng/ml |
基因名称 | MRC1 |
基因全名 | mannose receptor C-type 1 |
Uniprot ID | P22897 |
指标别名 | Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Human mannose receptor; Hmr; Macrophage mannose receptor 1-like protein 1; CD206; MRC1; CLEC13D; CLEC13DL; MRC1L1 |
背景资料 | The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages and immature dendritic cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. It is the first member of a family of endocytic receptors that includes Endo180 (CD280), M-type PLA2R, and DEC-205 (CD205). This gene is mapped to 10p12.33. The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. |
显色时间 | 15-20 |