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从猪脊髓中分离出的铃蟾肽样肽对大鼠子宫的平滑肌呈现有效的兴奋剂作用。
| 序列(三个字母） | H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 |
| 序列（一个字母） | GYPGKF-NH2 |
| CAS | [245443-52-1] |
| 纯度 | ≥95.0% |
| 分子量 | 667.7 |
| Description | Protease-activated receptor-4 activating peptide derived from murine PAR-4. This peptide was able to cause rat platelet aggregation with an EC50 value of 40 ?M. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes. The family of at least seven transmembrane G protein coupled receptors includes at least four receptor subtypes (PAR1, PAR2, PAR3, PAR4). PAR4 activating peptides, GYPGKF-NH2 and AYPGKG-NH2, produce concentration dependent contractile effects on the muscle. |
| Formula | C33H46N8O7 |
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