N-Y抗原表位之一已被鉴定为来源于SMCY的11个氨基酸肽SPSVDKARAEL,SMCY是Y染色体上编码的进化保守蛋白。 用该肽孵育的T2-B7细胞通过H-Y特异性CTL克隆进行裂解。 在10pM时达到半数最大裂解
序列(三个字母) | Ser-Pro-Ser-Val-Asp-Lys-Ala-Arg-Ala-Glu-Leu |
序列(一个字母) | SPSVDKARAEL |
纯度 | ≥95.0% |
分子量 | 1172.3 |
Description | One of the N-Y antigen epitopes has been identified as the 11 amino acid peptide SPSVDKARAEL derived from SMCY, an evolutionarily conserved protein encoded on the Y chromosome. T2-B7 cells incubated with this peptide were lysed by the H-Y specific CTL clone. Half maximal lysis was achieved at 10 pM |
Formula | C49H85N15O18 |
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