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MilliplexCatalogID.FMHMAG-29K-06.Feline

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号:FMHMAG-29K-06

牌:Millipore 密理博

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Analytes Available Species Reactivity Key Applications Detection Methods
Amylin (Total), Ghrelin (Active), GIP, GLP-1 (Active), Glucagon, Insulin, Leptin, Pancreatic Polypeptide (PP), PYY Fe Mplex Luminex xMAP
Description
Catalogue Number FMHMAG-29K
Trade Name
  • MILLIPLEX
Description MILLIPLEX MAP Feline Metabolic Hormone Magnetic Bead Panel, FMHMAG-29K
Overview EMD Millipore’s MILLIPLEX MAP Feline Metabolic Hormone Magnetic Bead Panel is a 9-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, tissue/cell lysates, and culture supernatant samples: Amylin (Total), Ghrelin (Active), GIP, GLP-1 (Active), Glucagon, Insulin, Leptin, PP and PYY.
Background Information Metabolic syndrome is a cluster of conditions that occur together, including increased blood pressure, elevated insulin levels, excess body fat around the waist and abnormal cholesterol levels.

Key features of metabolic syndrome include insulin resistance, glucose intolerance, hypertension, dyslipidemia and central obesity—all of which are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease and even premature death.

Adults with metabolic syndrome present a low-grade inflammation, whose link with obesity may be a production of pro- and anti-inflammatory factors. Consequently, research done in this area covers multi-faceted fields of cytokines, acute phase proteins, diabetes and obesity related hormones, as well as other cardiovascular disease biomarkers.
References
Product Information
Detection method Luminex xMAP
Configuration Design your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay: <10%
  • Inter-assay: <20%
Panel Type MAGNETIC Metabolism
Applications
Application The analytes available for this multiplex kit are: Amylin (Total), Ghrelin (Active), GIP, GLP-1 (Active), Glucagon, Insulin, Leptin, Pancreatic Polypeptide (PP), PYY.
Key Applications
  • Multiplexing
Application Notes This is an overnight incubation assay with a 1-hour incubation with detection antibodies requiring 25 µL of neat plasma or serum, or 25 µL cell culture supernatant per well.
Immediately after serum and plasma sample collection, add DPPIV inhibitor (for GLP-1 measurement), protease inhibitor cocktail (for Amylin measurement), Aprotinin (for Glucagon measurement) and/or serine protease inhibitor (for Active Ghrelin measurement).
This kit may be used for the analysis of all or any combination of the Feline Metabolic Hormone panel analytes in serum, plasma or tissue/cell lysate and culture supernatant.
Biological Information
Specificity Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Species Reactivity
  • Feline
Analytes Available
  • Amylin (Total)
  • Ghrelin (Active)
  • GIP
  • GLP-1 (Active)
  • Glucagon
  • Insulin
  • Leptin
  • Pancreatic Polypeptide (PP)
  • PYY
Cross Reactivity Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Accuracy
  • 93% - 104%
Physicochemical Information
Sensitivity
  • 0.9 - 225 pg/mL (+2SD)
  • Please see kit protocol for individual assay sensitivities.
Linearity of Dilution Contact technical support for this information
Standard Curve Range
  • Amylin (total): 41 – 30,000 pg/mL
  • Ghrelin (Active): 13.7 – 10,000 pg/mL
  • GIP: 1.4 – 1,000 pg/mL
  • GLP-1 (active): 2.7 – 2,000 pg/mL
  • Glucagon: 13.7 – 10,000 pg/mL
  • Insulin: 6.9 – 5,000 pg/mL
  • Leptin: 343 – 250,000 pg/mL
  • PP: 2.7 – 2,000 pg/mL
  • PYY: 13.7 – 10,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions Recommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size 96-well plate
Transport Information
Supplemental Information
Specifications

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