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Senescence Detection Kit

市场价：: 0.00

促销价：: ¥0.00

货号：QIA117-1KIT

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Detection Methods
Colorimetric

Description
Overview	Useful for the histochemical detection of senescent cells. The failure of cells to become senescent may lead to tumor progression. Higher levels of β-Galactosidase is considered as a good marker for senescent cells. The mechanism of this is believed to be due to the increased lysosomal content of senescent cells, resulting in an increase of the lysosomal enzyme β-galactosidase. Cells can be observed using microscope.
Catalogue Number	QIA117
Brand Family	Calbiochem®
Materials Required but Not Delivered	• PBS • DMF

References
References	Kurz, D.J., et al. 2000. J. Cell Sci. 113, 3613. Dimri, G.P., et al. 1995. Proc. Natl. Acad. Sci. USA 92, 9363.

Product Information
Detection method	Colorimetric
Form	250 Tests
Format	12-well plate
Kit contains	Fixative Solution, X-Gal, Staining Solution, Staining Supplement, and a user protocol.

Applications
Application References	Funasaka, T., et al. 2007. J. Biol. Chem. 282, 36362. Chen, Z., et al. 2005. Nature 436, 725.

Biological Information
Assay time	30 min. plus overnight incubation
Sample Type	Intact cells

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Intended use	The Calbiochem^® Senescence Detection Kit is useful for the histochemical detection of senescent cells. The failure of cells to become senescent may lead to tumor progression. The mechanism of this is believed to be the increased lysosomal content of senescent cells resulting in an increase of the lysosomal enzyme β-galactosidase.

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Multiple Toxicity Values, refer to MSDS
Storage	-20°C
Storage Conditions	Upon arrival store the entire contents of the kit at -20°C.
Protect from Light	Protect from light
Do not freeze	Ok to freeze

Packaging Information

Transport Information

Supplemental Information
Kit contains	Fixative Solution, X-Gal, Staining Solution, Staining Supplement, and a user protocol.

Specifications

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