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Qiagen 凯杰 Biosharp Omega

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Myeloperoxidase, Human Polymorphonuclear Leukocytes

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号:475911-100UG

牌:Millipore 密理博

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Replacement Information

重要规格表

Description
Overview Native, human myeloperoxidase from polymorphonuclear leukocytes. A lysosomal enzyme that catalyzes oxidations by hydrogen peroxide, including MPO-chloride-mediated killing of microbes and tumor cells, inactivation of chemotactic factors, and cross-linking of proteins. MPO catalyzes the formation of hypochlorous acid that kills bacteria either by binding the halide ion to intracellular constituents or by oxidation of bacterial lipids and proteins.
Catalogue Number 475911
Brand Family Calbiochem®
Synonyms MPO
References
References Nauseef, W.M., et al. 1998. J. Leukocyte Biol. 63, 264.
Panasenko, O.M., et al. 1994. Free Radic. Biol. Med. 16, 143.
Mulligan, M.S., et al. 1992. Br. J. Pharmacol. 107, 1159.
Sharonov, B.P., and Churilova, I.V. 1992. Biochem. Biophys. Res. Commun. 189, 1129.
Product Information
CAS number 9003-99-0
Unit of Definition One unit is defined as the amount of enzyme that will reduce 1.0 µmol H₂O₂ per min at 25°C, pH 6.0.
EC number 1.11.1.7
Form Lyophilized
Formulation Lyophilized from 100-700 mM NaCl, 50 mM sodium acetate buffer, pH 6.0.
Applications
Biological Information
Purity ≥95% by SDS-PAGE
Source Prepared from blood that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity 150-200 units/mg protein
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special Instructions Following reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 1 year at -20°C or -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

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