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Thrombin-Activatable Fibrinolysis Inhibitor, Human

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号:605197-50UG

牌:Millipore 密理博

账期 货到付款

EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Description
Overview Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. Circulates in plasma as a zymogen at a concentration of 50 nM. Activated by thrombin-thrombomodulin complex by proteolytic cleavage at Arg92. Believed to play an important role in interaction between the procoagulant, anticoagulant, and fibrinolytic systems.
Catalogue Number 605197
Brand Family Calbiochem®
Synonyms Plasma Procarboxypeptidase B, TAFI
References
References Boffa, M.B., et al. 1999. Biochemistry 38, 6547.
Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127.
Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.
Product Information
Unit of Definition One unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.
Form Liquid
Formulation In 150 mM NaCl, 20 mM HEPES, pH 7.4.
Applications
Biological Information
Purity ≥95% by SDS-PAGE
Source Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity ≥2-9 units/mg protein
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special Instructions Following initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

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