Coagulation Factor Xa, Human Plasma

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Coagulation Factor Xa, Human Plasma

市场价：: 0.00

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货号：233526-10U

品牌：Millipore 密理博

配送至：

北京朝阳

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数量：

EA (预计3-5工作日到货)

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Replacement Information

Description
Overview	Native coagulation factor Xa from human plasma prepared from homogeneous Factor X by activation with Russel’s viper venom. The venom is removed after activation. During coagulation, in the presence of Ca²⁺ and membrane phospholipids, a complex of Factor Xa and Factor Va (the prothrombinase complex) activates prothrombin to thrombin. Inhibitors include AEBSF (Cat. No. 101500), DFP (Cat. No. 30967), PMSF (Cat. No. 52332), and Soybean Trypsin Inhibitor (Cat. No. 650357). Sold on the basis of plasma equivalent units of Factor X. 100 plasma equivalent units are equal to 800 µg of Factor X.
Catalogue Number	233526
Brand Family	Calbiochem®

References
References	Heeb, M.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 2728. Lindhout, T., et al. 1994. Biochem. J. 297, 131. Morishita, H., et al. 1994. Thrombosis Res. 73, 193. Lupu, C., et al. 1993. Thrombosis Haemostasis 70, 579. Jordan, S.P., et al. 1992. Biochemistry 31, 5374. Schoen, P., et al. 1992. Br. J. Haemotol. 81, 255. Tracy, P.B., et al. 1992. Methods Enzymol. 215, 329. Lawson, J.H., and Mann, K.G. 1991. J. Biol. Chem. 226, 11317. Tans, G., et al. 1991. J. Biol. Chem. 266, 21864. Owen, W.G., et al. 1974. J. Biol. Chem. 249, 594.

References

Heeb, M.J., et al. 1994. Proc. Natl. Acad. Sci. USA 91, 2728.
Lindhout, T., et al. 1994. Biochem. J. 297, 131.
Morishita, H., et al. 1994. Thrombosis Res. 73, 193.
Lupu, C., et al. 1993. Thrombosis Haemostasis 70, 579.
Jordan, S.P., et al. 1992. Biochemistry 31, 5374.
Schoen, P., et al. 1992. Br. J. Haemotol. 81, 255.
Tracy, P.B., et al. 1992. Methods Enzymol. 215, 329.
Lawson, J.H., and Mann, K.G. 1991. J. Biol. Chem. 226, 11317.
Tans, G., et al. 1991. J. Biol. Chem. 266, 21864.
Owen, W.G., et al. 1974. J. Biol. Chem. 249, 594.

Product Information
CAS number	9002-05-5
Unit of Definition	One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol CHROMOZYM<sup>®</sup> X substrate per min at 25°C.
EC number	3.4.21.6
Form	Lyophilized
Formulation	Lyophilized from 700 mM NaCl, 20 mM Tris-HCl, pH 7.4.

Applications

Biological Information
Purity	homogeneous by SDS-PAGE
Source	Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity	≥170 units/mg protein

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.