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PARATHYROID HORMONE 1-34, HUMAN

市场价：: 0.00

促销价：: ¥0.00

货号：05-23-5501-1MG

品牌：Millipore 密理博

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北京朝阳

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EA (预计3-5工作日到货)

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Replacement Information

重要规格表

Empirical Formula	CAS #
C₁₈₁H₂₉₁N₅₅O₅₁S₂	52232-67-4

Description
Overview	N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca²⁺ and phosphate metabolism. Regulates Ca²⁺ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca²⁺ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca²⁺ and stimulates renal hydroxylation of 25-(OH)-Vitamin D₃ to 1,25-(OH)₂-Vitamin D₃. Increases the production of inhibitory IGF binding protein 4 in bone cells.
Catalogue Number	05-23-5501
Brand Family	Calbiochem®

References
References	Matsui, H., et al. 1995. Am. J. Physiol. 268, R21. Dua, K., et al. 1994. Exp. Physiol. 79, 401.

Product Information
CAS number	52232-67-4
ATP Competitive	N
Form	White to off-white lyophilized solid
Formulation	Supplied as an trifluoroacetate salt.
Hill Formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Chemical formula	C₁₈₁H₂₉₁N₅₅O₅₁S₂
Reversible	N
Sold on the basis of peptide content	Y

Applications

Biological Information
Primary Target	Homeostatic control of Ca2+ and phosphate metabolism
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Peptide Content	Y
Peptide Sequence	H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

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